Biosensors based on nanomaterials are becoming a crucial element for rapid point-of-care diagnosis. In this work, we test different nanomaterials for body vital signs monitoring such as glucose level, and for detection of different diseases. Novel fabrication processes are investigated along with biosensor sensitivity and accuracy. Our goal is to make affordable biosensors with high sensitivity for rapid testing. We demonstrate highly sensitive and conformal Indium Oxide nanoribbon Field-Effect-Transistor biosensors with a fully integrated on-chip gold side gate, which have been laminated onto various surfaces, such as artificial arms and watches, and have enabled glucose detection in various body fluids, such as sweat and saliva. The shadow-mask-fabricated devices show good electrical performance with gate voltage applied using a gold side gate electrode and through an aqueous electrolyte. The resulting transistors show a high on−off ratio and good mechanical robustness. With the electrodes functionalized with glucose oxidase, chitosan, and single-walled carbon nanotubes, the glucose sensors show a very wide detection range spanning at least 5 orders of magnitude and a detection limit down to 10 nM.